The decision to terminate the HYPERION trial reflects a loss of clinical equipoise, making it unethical to continue the placebo-controlled study.

Patients with ATTR-PN have a high rate of comorbidities and substantial direct healthcare and economic burdens, a study found.

Associations between therapies and quality of life (QoL) in patients with generalized pustular psoriasis (GPP) can differ substantially.

The phase 1 trial is testing the safety tolerability, pharmacokinetics, and pharmacodynamics of PVT201 in healthy volunteers and patients.

EGPA-associated nasal polyposis should be managed with medically (ie, biologics, anti-inflammatory drugs, and topical corticosteroids) and, in some cases, surgery. Nasal polyposis associated with ...

Women who desire to become pregnant should be counseled on the significance of alloimmunization as a substantial risk during pregnancy. A pregnant woman with hemolytic disease of the fetus and newborn ...

Which of the statements below about the diagnosis of chronic lymphocytic leukemia (CLL) are correct? Select one of the options for each question, then submit your answers to see how well you scored ...

Pregnancies affected by multiple alloantibodies had significantly higher antibody titers and an increased need for intrauterine transfusion. Pregnancies complicated by multiple alloantibodies rather ...

In diagnosed cases of cutaneous mastocytosis, investigations to rule out systemic mastocytosis may be appropriate. A young child with a small chest lump and anemia was found to have cutaneous ...

Which of the statements below about the genetics of generalized pustular psoriasis (GPP) are correct? Select one of the options for each question, then submit your answers to see how well you scored ...

Children with achondroplasia seem to be more challenged in the anterior-posterior direction, which might be linked to an anterior-shifted pelvis. No difference was observed in bipedal static postural ...