Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

Scientists have discovered that the peptide hormone adrenomedullin plays a pivotal role in obesity-related type 2 diabetes, ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.

Genetic engineering deployed to insert gene for human insulin into a bacterium, thus harnessing the substance for widespread ...

Pluristyx has developed a clinical-grade manufacturing process for using a licensed Mad7 gene editing technology to block Human Leukocyte Antigen (HLA) markers expression. Humacyte is optimizing a ...

But the genetically engineered rodents were unable to reproduce. Chinese researchers used embryonic stem cell engineering to create bi-paternal mice - ones with two male parents. Their research, ...

It is not possible to change some risk factors for insulin resistance and type 2 diabetes, such as genetic factors and family history. However, a person can take some steps to reduce the ...

Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations ... Jacobs School of Engineering There are two ...

"We can see that people with this genetic variant have insulin-resistant musculature. This means that their muscle tissue responds poorly to insulin, which is critical, as muscles account for the ...

Patients are being offered transplants of genetically modified insulin-producing cells and the initial results are promising. We put a few questions to Per-Ola Carlsson, Professor of Medical Cell ...

Even though a large proportion of cancer patients carry genetic mutations that make them more susceptible to cancer, only a small percentage of them — and their family members — undergo ...