A nonfunctional mutant of a reporter gene (W in the figure) is introduced or is present in a cell (a). In the recombinant targeting vector (b), the viral genes are replaced by a sequence that is ...

Conditional gene targeting based on excision or inversion of loxP-flanked DNA segments by Cre recombinase is a powerful technology for the analysis of gene function, but unexpected expression ...

New research published in Developmental Cell provides evidence that targeting the KCNB2 gene could enhance current cancer treatments, tackling medulloblastoma tumour growth. "Tumour-propagating ...

The University of Southern California (USC) has received a $6m grant from the California Institute for Regenerative Medicine (CIRM) to advance a new gene therapy for glioblastoma. The treatment is ...

Gene technology has been earmarked for expansion in New Zealand, but without robust regulation local communities could be left with the unintended consequences.